Diagnostic and Clinical Significance of Serum Levels of D-Lactate and Diamine Oxidase in Patients with Crohn’s Disease
Table 1
General characteristics of 59 patients with CD.
Characteristics
CD active ()
CD remission ()
value
Age in years, mean (range)
37.2 (20-47)
39.6 (17-55)
0.408
Sex: male, (%)
13 (45)
17 (57)
0.363
Duration of disease in years, median (IQR)
7 (2-11)
7.5 (3-13)
0.504
Smoking history, (%)
0.626
Current
8 (27)
6 (20)
Former
10 (34)
9 (30)
Never
11 (38)
15 (50)
Site of disease, (%)
0.605
Ileal (L1)
2 (7)
1(3)
Colonic (L2)
13 (45)
17(57)
Ileocolonic (L3)
14 (48)
12(40)
Drugs before inclusion, (%)
0.450
Mesalamine
5 (17)
3 (10)
Azathioprine/6-MP
7 (24)
5 (17)
Anti-TNF
10 (34)
9 (30)
Anti-TNF and azathioprine/6-MP
7 (24)
13 (43)
Number of prior surgeries, mean (range)
0.20 (0-2)
0.28 (0-3)
0.898
Having extraintestinal manifestations, (%)
2 (6)
1 (3)
0.612
CD: Crohn’s disease; 6MP: 6-mercaptopurine; IQR: interquartile range. There were no significant differences between groups in the active stage CD patients and remission stage CD patients.