Safety of Simultaneous Hepatectomy and Splenectomy in the Treatment of Hepatocellular Carcinoma Complicated with Hypersplenism: A Meta-analysis

Table 1

Basic characteristics of all studies pooled in the meta-analysis.

Study	Year	County	Groups	No. of patients ()	No. of male ()	Mean age	Child-Pugh classification			Tumor number		Type of hepatectomy
							A	B	C	Solitary	Multiple	Minor^†	Major^‡
Cao et al. [19]	2003	China	HS	11	11	46	6	5	0	NA	NA	NA	NA
			HA	15	14	41	7	8	0	NA	NA	NA	NA
Li et al. [12]	2014	China	HS	60	46	55.2	52	8	0	47	13	49	11
			HA	121	100	55.8	107	14	0	102	19	95	26
Luo et al. [24]	2010	China	HS	16	NA	NA	14	2	0	NA	NA	NA	NA
			HA	14	NA	NA	10	4	0	NA	NA	NA	NA
Oh et al. [25]	2003	Korea	HS	12	9	48.8	6	6	0	NA	NA	7	5
			HA	6	4	58.7	4	2	0	NA	NA	3	3
Wang et al. [27]	2012	China	HS	31	25	48.94	26	5	0	NA	NA	NA	NA
			HA	30	24	52.33	25	5	0	NA	NA	NA	NA
Luo et al. [23]	2014	China	HS	57	49	49.7	51	6	0	44	13	41	10
			HA	114	106	49.5	105	9	0	94	20	91	20
Zhang et al. [13]	2017	China	HS	110	91	50.19	NA	NA	NA	100	10	99	11
			HA	271	229	49.99	NA	NA	NA	239	32	227	44
Feng et al. [21]	2011	China	HS	12	8	53.12	9	3	0	11	1	NA	NA
			HA	23	17	51.32	19	4	0	22	1	NA	NA
Shan et al. [26]	2009	China	HS	29	26	47.24	15	12	1	25	4	NA	NA
			HA	29	28	53.21	28	0	0	22	7	NA	NA
Huo et al. [22]	2006	China	HS	17	NA	NA	NA	NA	NA	NA	NA	NA	NA
			HA	7	NA	NA	NA	NA	NA	NA	NA	NA	NA
Chen et al. [20]	2005	China	HS	94	80	44.6	64	30	0	75	19	90	4
			HA	110	89	41.7	61	49	0	82	28	103	7
Bi et al. [17]	2010	China	HS	71	59	54	65	6	0	NA	NA	52	19
			HA	106	91	57	96	10	0	NA	NA	82	24
Cai et al. [18]	2004	China	HS	57	40	55.6	48	9	0	NA	NA	45	12
			HA	45	34	50.8	42	3	0	NA	NA	36	9

^†Minor hepatectomy = irregular hepatectomy and resection of one or two hepatic segments; ^‡major hepatectomy = resection of three or more hepatic segments. Abbreviations: HS: simultaneous hepatectomy and splenectomy; HA: hepatectomy alone; NA: not available.