Research Article
Immuno-Inflammatory Characteristics in Low Severity COVID-19 Patients with Digestive Symptoms
Table 3
Inflammation and immune characteristics based on the classification of main symptoms in COVID-19 patients on admission.
| | Items | Total | Digestive Only | Respiratory Only | Digestive+Respiratory | |
| | WBC (G/L) | 5.54 (1.73-11.64) | 5.65 (2.66-11.64) | 5.44 (1.73-10.24) | 5.58 (2.42-10.48) | 0.789 | | <9.5 G/L | 196 (95.1%) | 46 (95.8%) | 84 (94.4%) | 66 (95.7%) | 0.906 | | >9.5 G/L | 10 (4.9%) | 2(4.2%) | 5 (5.6%) | 3 (4.3%) | | | Neutrophil (G/L) | 3.58 (0.93-8.67) | 3.61 (1.36-8.1) | 3.51 (0.93-8.56) | 3.65 (1.13-8.67) | 0.854 | | <6.3 G/L | 191 (92.7%) | 45 (93.7%) | 82 (92.1%) | 64 (92.8%) | 0.941 | | >6.3 G/L | 15 (7.3%) | 3 (6.3%) | 7 (7.9%) | 5 (7.2%) | | | Lymphocyte (G/L) | 1.35 (0.28-3.4) | 1.41 (0.42-2.18) | 1.28 (0.28-3.4) | 1.39 (0.39-2.76) | 0.302 | | <1.1 G/L | 69 (33.5%) | 16 (33.3%) | 34 (38.2%) | 19 (27.5%) | 0.371 | | ≥1.1 G/L | 137 (66.5%) | 32 (66.7%) | 55 (61.8%) | 50 (72.5%) | | | Procalcitonin (ug/L) | 0.14 (0.03-2.99) | 0.13 (0.03-2.99) | 0.14 (0.03-2.99) | 0.14 (0.03-2.99) | 0.139 | | <0.5 ug/L | 183 (88.8%) | 42 (87.5%) | 80 (89.9%) | 61 (88.4%) | 0.906 | | ≥0.5 ug/L | 23 (11.2%) | 6 (12.5%) | 9 (10.1%) | 8 (11.6%) | | | C-reactive protein (mg/L) | 20.5 (0.3-173) | 19.3 (0.6-173) | 26.2 (0.3-136) | 21.8 (0.6-168) | 0.569 | | <8 mg/L | 90 (51.4%) | 27 (62.8%) | 31 (40.3%) | 32 (58.2%) | 0.029 | | ≥8 mg/L | 85 (48.6%) | 16 (37.2%) | 46 (59.7%) | 23 (41.8%) | | | ESR (mm/h) | 42.1 (2-140) | 38.2 (7-99) | 46.8 (2-140) | 38.5 (2-112) | 0.357 | | <15 mm/h | 35 (19.7%) | 6 (15.0%) | 14 (17.9%) | 15 (25.0%) | 0.411 | | ≥15 mg/L | 143 (80.3%) | 34 (85.0%) | 64 (82.1%) | 45 (75.0%) | | | Inflammatory cytokines | | | | | | | IL-2 (0.1-4.1 pg/ml) | 2.66 (2.07-4.93) | 2.92 (2.07-4.93) | 2.62 (1.85-4.08) | 2.59 (1.82-3.98) | <0.001 | | IL-4 (0.1-3.2 pg/ml) | 2.32 (0.98-8.23) | 2.57 (1.04-8.23) | 2.15 (1.00-4.18) | 2.00 (0.98-4.80) | 0.002 | | IL-6 (0.1-2.9 pg/ml) | 40.09 (1.96-437.81) | 45.53 (1.96-437.81) | 43.18 (2.27-424.93) | 31.64 (2.05-383.95) | 0.559 | | <2.9 pg/ml | 10 (5.3%) | 4 (8.5%) | 3 (3.7%) | 3 (5.0%) | 0.610 | | 2.9-90 pg/ml | 159 (84.6%) | 37 (78.7%) | 69 (85.2%) | 53 (88.3%) | | | ≥90 pg/ml | 19 (10.1%) | 6 (12.8%) | 9 (11.1%) | 4 (6.7%) | | | IL-10 (0.1-5.0 pg/ml) | 3.84 (1.75-15.98) | 4.42 (2.15-15.98) | 3.75 (1.92-9.34) | 3.46 (1.75-6.30) | 0.021 | | TNF-a (0.1-23 pg/ml) | 5.76 (0.90-67.26) | 4.19 (1.01-21.26) | 7.40 (0.90-67.26) | 4.78 (1.27-20.73) | 0.014 | | Immune system indexes | | | | | | | IgG (7.51-15.6 g/L) | 11.53 (7.3-16.8) | 11.39 (7.30-16.80) | 11.67 (8.15-16.60) | 11.56 (6.83-19.30) | 0.912 | | IgM (0.46-3.04 g/L) | 1.32 (23.8%) | 1.06 (0.50-2.31) | 1.68 (0.39-12.03) | 1.03 (0.46-1.96) | 0.200 | | C3 (0.79-1.52 g/L) | 0.91 (14.6%) | 0.94 (0.64-1.24) | 0.90 (0.53-1.24) | 0.91 (0.71-1.10) | 0.684 | | C4 (0.16-0.38 g/L) | 0.23 (6.4%) | 0.23 (0.14-0.41) | 0.24 (0.08-0.41) | 0.19 (0.03-0.29) | 0.055 | | CD3+T lymphocytes (58.17-84.22%) | 73.07 (26.12-93.02) | 73.67 (45.44-93.02) | 72.12 (49.40-85.88) | 73.10 (26.12-92.20) | 0.996 | | CD4+T lymphocytes (25.34-54.37%) | 46.69 (10.70-75.73) | 48.87 (24.19-75.73) | 47.62 (35.22-64.48) | 44.67 (10.70-70.46) | 0.186 | | CD8+T lymphocytes (14.23-38.95%) | 22.47 (5.09-58.88) | 21.40 (7.57-38.74) | 21.33 (7.27-34.99) | 23.78 (5.09-58.88) | 0.282 |
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