Impact of Hepatic Steatosis on the Antiviral Effects of PEG-IFNα-2a in Patients with Chronic Hepatitis B and the Associated Mechanism

Figure 2

The distribution of HBcAg in the hepatocytes of CHB patients was classified into four types. (a) The HBcAg-negative type showed no HBcAg expression in either the nucleus or cytoplasm of the hepatocytes (immunohistochemical stain for HBcAg, ×200). (b) The cHBcAg type showed HBcAg expression only in the cytoplasm but not in the nucleus of hepatocytes (immunohistochemical stain for HBcAg, ×200). (c) The cdHBcAg type showed more than 2/3 HBcAg expression in the cytoplasm of hepatocytes (immunohistochemical stain for HBcAg, ×200). (d) The mHBcAg type showed 50% HBcAg expression in the nucleus and 50% HBcAg expression in the cytoplasm of the hepatocytes (immunohistochemical stain for HBcAg, ×200).

(a)

(b)

(c)

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