Research Article

Previous Intestinal Resection Is Associated with Postoperative Complications in Crohn’s Disease: A Cohort Study

Table 4

Risk factors associated with postoperative complications.

VariablesUnremarkable postoperative course ()Any postoperative complications () value

Univariate analysis
Previous intestinal resection for CD, no. (%)29 (39.19)33 (60.00)0.019
Male, no. (%)36 (48.65)30 (54.55)0.508
Age at surgery, mean (SD) (y)38.90 (9.96)38.60 (7.90)0.851
BMI, mean (SD)18.10 (1.20)17.82 (1.06)0.171
Disease duration since diagnosis, mean (SD) (y)7.37 (4.45)7.94 (3.45)0.433
Disease behavior, no. (%)0.712
 B1: nonstricturing, nonpenetrating14 (18.92)12 (21.82)
 B2: stricturing28 (37.84)17 (30.91)
 B3: penetrating32 (43.24)26 (47.27)
Disease location, no. (%)0.211
 L1: terminal ileum22 (29.73)20 (36.36)
 L2: colon13 (17.57)15 (27.27)
 L3: ileocolon34 (45.95)18 (32.73)
 L4: upper gastrointestinal tract5 (6.76)2 (3.64)
Perianal disease, no. (%)16 (21.62)15 (27.27)0.458
Preoperative descriptions, no. (%)
 Biologics17 (22.97)19 (34.55)0.147
 5-ASA/sulfasalazine16 (21.62)20 (36.36)0.065
 Steroids14 (18.92)20 (36.36)0.026
 Immunomodulators16 (21.62)15 (27.27)0.458
Indications for surgery, no. (%)0.302
 Unresponsiveness to medical management10 (13.51)14 (25.45)
 Bowel fistula(e) with or without disease-related abscess(es)32 (43.24)18 (32.73)
 Fibrosis/stricturing26 (35.14)20 (36.36)
 Other6 (8.11)3 (5.45)
ASA score, no. (%)0.003
 120 (27.03)6 (10.91)
 239 (52.70)24 (43.64)
 312 (16.22)22 (40.00)
 43 (4.05)3 (5.45)
Surgical procedures, no. (%)0.259
 Small-bowel resection27 (36.49)18 (32.73)
 Ileocolic resection29 (39.19)15 (27.27)
 Segmental colectomy9 (12.16)12 (21.82)
 Other (ostomy closure, strictureplasty, stoma creation without resection)9 (12.16)10 (18.18)
Surgical technique, no. (%)0.139
 Laparoscopy39 (52.70)21 (38.18)
 Open surgery18 (24.32)22 (40.00)
 Conversion17 (22.97)12 (21.82)
Intraoperative findings, no. (%)
 Fistula(e)23 (31.08)24 (43.64)0.143
 Abscess(es)15 (20.27)16 (29.09)0.246
 Duration of operation, mean (SD) (min)121.72 (26.04)126.69 (24.85)0.276
 Estimated blood loss, mean (SD) (mL)133.85 (43.49)156.89 (61.90)0.014
 Length of hospital stay, mean (SD) (d)9.34 (2.87)13.88 (7.46)<0.001

CD: Crohn’s disease; BMI: body mass index; 5-ASA: 5-aminosalicylic acid: ASA: American Society of Anesthesiologists.