Protective Role of Somatostatin in Sepsis-Induced Intestinal Barrier Dysfunction through Inhibiting the Activation of NF-κB Pathway

Figure 3

JSH-23 enhanced the protective effect of SST on sepsis-induced intestinal barrier dysfunction. (a) Intestinal tissue from the control, sham, model, model+SST group, model+SST+JSH-23 group, and model+JSH-23 group was detected using hematoxylin and eosin (HE) staining. Sections presented ten mice in each group. Magnification: 100x. Scale bar: 200 μm. (b–d) Detection of inflammatory factors, including TNF-α, IL-6, and IL-10, in the ileum using ELISA. Data were shown as the from 3 independent experiments. , vs. sham; ^#; ^###, vs. model. ^{^}P <0.05, vs. model+SST. ^△P <0.05, ^△△, vs. model+SST+JSH-23. SST: somatostatin.

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