Research Article
Tumor Size as a Critical Prognostic Factor in T1-2 Stage Esophageal Cancer
Table 1
Baseline characteristics of esophagus cancer patients by T stage.
| | All (%) | T1 (%) | T2 (%) | T3 (%) | T4 (%) | TX (%) |
| | Age (year) | 65.6 | 66.7 | 65.9 | 64.8 | 63.9 | 67.3 | | Sex | | | Male | 14192 (79.5) | 3732 (78.7) | 1521 (74.3) | 5177 (81.4) | 1873 (79.0) | 1889 (78.0) | | Female | 3653 (20.5) | 1013 (21.3) | 527 (25.7) | 1181 (18.6) | 498 (21.0) | 534 (22.0) | | Histology | | | SCN | 5862 (32.8) | 1482 (31.2) | 601 (29.3) | 1898 (29.9) | 1018 (42.9) | 863 (35.6) | | ANA | 10442 (58.5) | 2889 (60.9) | 1223 (59.7) | 3896 (61.3) | 1112 (46.9) | 1322 (54.6) | | EN | 568 (3.2) | 165 (3.5) | 30 (1.5) | 127 (2.0) | 110 (4.6) | 136 (5.6) | | CMSN | 812 (4.6) | 180 (3.8) | 77 (3.8) | 373 (5.9) | 108 (4.6) | 74 (3.1) | | CEN | 161 (0.9) | 29 (0.6) | 17 (0.8) | 64 (1.0) | 23 (1.0) | 28 (1.1) | | Grade | | | Grade I | 898 (5.0) | 359 (7.6) | 107 (5.2) | 257 (4.0) | 99 (4.2) | 76 (3.1) | | Grade II | 6481 (36.3) | 1832 (38.6) | 841 (41.1) | 2275 (35.8) | 784 (33.1) | 749 (30.9) | | Grade III-IV | 7786 (43.6) | 1781 (37.5) | 737 (36.0) | 3033 (47.7) | 1066 (45.0) | 1169 (48.2) | | Unknown | 2680 (15.0) | 773 (16.3) | 263 (12.8) | 793 (12.5) | 422 (17.8) | 429 (17.7) | | N stage | | | N0 | 3491 (19.6) | 1181 (24.9) | 605 (29.5) | 1473 (23.2) | 177 (7.5) | 54 (2.2) | | N1 | 1416 (8.0) | 239 (5.0) | 229 (11.2) | 808 (12.7) | 111 (4.7) | 29 (1.2) | | N2 | 645 (3.6) | 39 (0.8) | 74 (3.6) | 474 (7.5) | 54 (2.3) | 4 (0.2) | | N3 | 346 (1.9) | 9 (0.2) | 21 (1.0) | 269 (4.2) | 44 (1.9) | 3 (0.1) | | NX | 11837 (66.3) | 3258 (68.7) | 1010 (49.3) | 3304 (52.0) | 1974 (83.3) | 2291 (94.6) | | M stage | | | M0 | 12321 (69.0) | 3498 (73.7) | 1686 (82.3) | 5103 (80.3) | 1207 (50.9) | 827 (34.1) | | M1 | 5368 (30.1) | 1247 (26.3) | 262 (12.8) | 1255 (19.7) | 1164 (49.1) | 1440 (59.4) | | MX | 156 (0.9) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 156 (6.4) | | Tumor size (cm), median (IQR) | 5.01 (3.0-6.5) | 4.04 (1.8-5.2) | 4.18 (2.2-5.0) | 5.16 (3.2-6.5) | 6.38 (4.0-8.0) | 5.85 (4.0-7.2) | | LNE | | | 0-2 | 12458 (69.8) | 3441 (27.6) | 1110 (54.2) | 3546 (55.8) | 2042 (86.1) | 2319 (95.7) | | >2 | 5169 (28.7) | 1252 (24.4) | 812 (39.6) | 2746 (43.2) | 304 (12.8) | 55 (2.3) | | Surgery status | | | No surgery | 11468 (64.3) | 2863 (25.0) | 984 (48.0) | 3307 (52.0) | 2007 (84.6) | 2307 (95.2) | | Local tumor ED | 502 (2.8) | 400 (80.0) | 28 (1.4) | 28 (0.4) | 199 (8.4) | 27 (1.1) | | Esophagectomy | 1508 (8.5) | 412 (27.3) | 262 (12.8) | 732 (11.5) | 74 (3.1) | 28 (1.1) | | Esophagectomy LG | 4319 (24.2) | 1050 (24.3) | 670 (32.7) | 2283 (35.9) | 267 (11.3) | 49 (2.0) |
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