Prevalence of Elevated Alanine Aminotransferase by Diagnostic Criterion, Age, and Gender among Adolescents
Table 4
Univariate and multivariate logistic regression analyses with elevated alanine aminotransferase (ALT) as the outcome variable, based on the diagnostic criterion II (>40 U/L for boys and girls).
Variable
Univariate analysis
Multivariate analysisa
Wald test
OR (95% CI)
value
Wald test
OR (95% CI)
value
Girls (vs. boys)
46.388
0.29 (0.21-0.42)
<0.001
21.129
0.42 (0.29-0.60)
<0.001
Age (years)
28.711
<0.001
16.540
0.011
10–11
1.00
1.00
12
4.315
2.32 (1.05-5.12)
0.038
3.872
2.32 (1.00-5.38)
0.049
13
8.054
3.62 (1.49-8.78)
0.005
9.492
4.31 (1.70-10.92)
0.002
14
11.940
3.94 (1.81-8.56)
0.001
7.945
3.24 (1.43-7.35)
0.005
15
15.808
4.50 (2.14-9.43)
<0.001
8.593
3.21 (1.47-6.99)
0.003
16
19.030
5.38 (2.53-11.44)
<0.001
11.086
3.90 (1.75-8.69)
0.001
17
12.346
5.40 (2.11-13.82)
<0.001
10.645
5.34 (1.95-14.60)
0.001
Constant
—
—
—
268.333
—
<0.001
Boys or 10–11 years as the reference group; OR (95% CI): odds ratio (95% confidence interval). aAdjusted for gender, age, and body mass index using a multivariable logistic regression analysis.
