Research Article

Prevalence of Elevated Alanine Aminotransferase by Diagnostic Criterion, Age, and Gender among Adolescents

Table 5

Summaries of the prevalence of elevated ALT among adolescents for serum alanine aminotransferase (ALT) worldwide.

No.StudyCountryTarget populationAge (years)Sample sizeDefinition (U/L)Prevalence of elevated ALT

1Kim et al. [21]
(2018)
KoreaAdolescents10-188455>305.3% in total
8.0% in boys
2.1% in girls
>402.8% in total
>33 for boys
>25 for girls
5.4% in total

2Ruhl and Everhart [18]
(2013)
U.S.Adolescents12-199361>31 for boys
>24 for girls
10.8% am and 11.3% pm in boys
7.3% am and 7.8% pm in girls

3Kong et al. [35]
(2008)
ChinaAdolescents12-182102>403.2% in total
>305.9% in total

4Fraser et al. [19]
(2007)
U.S.Adolescents12-195586>308.0% in total
5.6% in boys
1.6% in girls
7.4% in white
11.5% in Mexican Americans
6.0% in black
10.6% in multiracial and other Hispanics
>403.6% in total
5.6% in boys
1.6% in girls
3.1% in white
6.1% in Mexican Americans
2.3% in black

5Strauss et al. [20]
(2000)
U.S.Overweight and obese adolescents12-182450>306% in overweight
20% in obesity

6Park et al. [12]
(2005)
KoreaAdolescents10-191594>403.6% in boys
2.8% in girls

7Wu et al. [10]
(2012)
ChinaStudents12-246997≥403.1% in total
4.8% in boys
1.5% in girls

8Park et al. [33]
(2012)
KoreaAdolescents12-181591>33 for boys
>25 for girls
5.9% in total
15.7% in overweight
34.9% in obesity

9Fermin et al. [17]
(2017)
U.S.Adolescents12-195411>309.14% in total
8.74% in non-Hispanic white
5.49% in non-Hispanic black
13.33% in Hispanic
>22 for girls
>25 for boys
16.25% in total

10DeBoer et al. [42]
(2013)
U.S.Adolescents12-194124>309.0% in total
13.7% in Hispanics
8.6% in non-Hispanic white
5.4% in non-Hispanic blacks

11Ramirez-Lopez et al. [22]
(2018)
MexicoAdolescents14-19674>403.0% in total
14.1% in obesity
1.81% in nonobesity

12Purcell et al. [23]
(2013)
MexicoYouth8-191262>409.8% in boys
3.8% in girls
28.9% in obesity
14.2% in overweight
40.0% in metabolic syndrome boys
14.5% in metabolic syndrome girls

13Elizondo-Montemayor et al. [32]
(2014)
MexicoObese and overweight children6-12236>4017.7% in total

14Samani et al. [25]
(2011)
IranChildren and adolescents6-181172>30 for boys
>19 for girls
4.9% in boys
7.45% in girls

15Wang et al. [43]
(2018)
KoreaHealthy adolescents10-181785>24.1 for boys
>17.7 for girls
14.9% in boys
12.3% in girls

16van Vliet et al. [24]
(2009)
NetherlandsOverweight and obese children3-18443>3020.3% in total
25.8% in boys
13.8% in girls

17Park et al. [28]
(2013)
KoreaAdolescents10-182242>30 for boys
>19 for girls
7.9% in boys
10.2% in girls