Gastroenterology Research and Practice / 2020 / Article / Tab 2 / Research Article
Diagnosis of Biliary Strictures Using Probe-Based Confocal Laser Endomicroscopy under the Direct View of Peroral Cholangioscopy: Results of a Prospective Study (with Video) Table 2 Summary of primary outcomes.
Diagnosis modality ( ) Sensitivity (%) 95% CI Specificity (%) 95% CI NPV (%) 95% CI PPV (%) 95% CI Accuracy (%) 95% CI (1) ERCP alone 15/17 (88.2) 65.7-97.9 6/13 (46.2) 23.3-70.9 6/8 (75) 40.9-95.6 15/22 (68.2) 47.3-83.6 21/30 (70) 52.1-83.3 (2) POCS 17/17 (100) 81.6-100 10/13 (76.9) 49.7-91.8 10/10 (100) 72.2-100 17/20 (85) 64.0-94.8 27/30 (90) 74.4-96.5 (3) pCLE under the direct view of POCS 16/17 (94.1) 73.0-99.7 12/13 (92.3) 66.7-99.6 12/13 (92.3) 66.7-99.6 16/17 (94.1) 73.0-99.7 28/30 (93.3) 78.7-98.8 (4) Tissue sampling under the direct view of POCS 14/17 (82.4) 59.0-93.8 13/13 (100) 77.2-100 13/16 (81.3) 57.0-93.4 14/14 (100) 78.5-100 27/30 (90) 74.4-96.5 (2) vs. (3), value 0.50 0.59 >0.99 (3) vs. (4), value 0.60 >0.99 >0.99
CI: confidence interval; NPV: negative predictive value; PPV: positive predictive value; ERCP: endoscopic retrograde cholangiopancreatography; pCLE: probe-based confocal laser endomicroscopy; POCS: peroral cholangioscopy.