Daily Usage of Proton Pump Inhibitors May Reduce the Severity of Critical Upper Gastrointestinal Bleeding in Elderly Patients

Figure 1

Comparisons of the clinical manifestation of upper gastrointestinal bleeding (estimated amount of bleeding, shock index, and total amount of blood transfusion) between 17 patients with and 80 patients without daily usage of proton pump inhibitors (PPIs). The mean estimated bleeding volume and SI in the habitual PPI users were both significantly less than those among the non-habitual users, respectively (). Meanwhile, there was no significant difference in the average volume of packed red blood cell volume transfused while being hospitalized between patients’ groups of habitual or nonhabitual PPI users ().