Review Article

Association between Inflammatory Bowel Disease and Pancreatitis: A PRISMA-Compliant Systematic Review

Table 1

Characteristics of included studies.

SourceCountryStudy designExposed group (cohort study)/case group (case-control study)Control groupOdds ratio (CI)Quality assessment (Newcastle-Ottawa scale)
Ulcerative colitisCrohn disease

Munk et al. [19] 2004DenmarkCase-control study1590 patients with acute pancreatitis from the Hospital Discharge Registry of the North Jutland County of Denmark from 1991 to 2002 (830 male, 760 female)15913 patients from the Central Personal Registry, matched by age and gender (8304 male, 7609 female)1.50 (0.70-3.60)3.70 (1.90-7.60)Selection: 4
Comparability: 2
Exposure: 3
Chen et al. [27] 2016ChinaCase-control study11909 patients diagnosed with IBD between 2000 and 2010 from the National Health Insurance Research Database of Taiwan (6418 male, 5491 female)A comparison cohort comprised 47636 age-matched patients without IBD (25672 male, 21964 female)2.49 (1.91-3.26)3.40 (2.70-4.28)Selection: 3
Comparability: 2
Exposure: 3
Chen et al. [28] 2017ChinaCohort study17796 patients with newly diagnosed chronic pancreatitis between 2000 and 2010 (14685 male, 3111 female)71164 matched patients without chronic pancreatitis (58720 male, 12444 female)2.80 (1.00-7.86)12.9 (5.15-32.50)Selection: 4
Comparability: 1
Outcome: 3

NHIS: National Health Information Service; IBD: inflammatory bowel disease; CI: confidence interval.