Gastric Carcinoma in Young Patients and Its Clinicopathological Characteristics and Prognosis

Table 5

Univariate and multivariate predictors of overall survival.

Variables	Univariate OR (95% CI)	value	Multivariate OR (95% CI)	value
Age
≤35	1
35-40	0.728 [0.349; 1.515]	0.395
41-60	0.663 [0.328; 1.339]	0.663
61-75	0.839 [0.415; 1.698]	0.839
Sex
Male	1
Female	0.993 [0.831; 1.188]	0.942
Resection margin
R0	1		1
R1/R2	3.860 [3.167; 4.703]	<0.001	2.167 [1.751; 2.682]	<0.001
Tumor location
U	1		1
M	0.817 [0.624; 1.070]	0.142	0.778 [0.588; 1.012]	0.061
L	0.692 [0.575; 0.832]	<0.001	0.795 [0.659; 0.959]	0.016
UML	3.913 [2.480; 6.173]	<0.001	1.389 [0.844; 2.286]	0.196
Macroscopic type
EGC	1
Types 1-2	4.129 [2.848; 5.987]	<0.001
Types 3-4	6.337 [4.371; 9.186]	<0.001
Differentiate degree
G1 and G2	1
G3 and G4	1.654 [1.278; 2.140]	<0.001
Tumor size (cm)
0-2	1		1
2-5	2.456 [1.664; 3.626]	<0.001	1.307 [0.869; 1.965]	0.198
5-8	4.485 [3.026; 6.648]	<0.001	1.615 [1.058; 2.463]	0.026
>8	7.852 [5.090; 12.112]	<0.001	1.727 [1.067; 2.797]	0.026
T stage
T1	1		1
T2	1.638 [1.003; 2.675]	<0.048	1.125 [0.680; 1.863]	0.647
T3	3.230 [1.659; 6.289]	<0.001	2.091 [1.059; 4.127]	0.034
T4	5.884 [4.093; 8.459]	<0.001	2.572 [1.709; 3.870]	<0.001
N stage
N0	1		1
N1	2.002 [1.505; 2.664]	<0.001	1.506 [1.123; 2.020]	0.005
N2	2.651 [2.032; 3.460]	<0.001	1.708 [1.289; 2.263]	<0.001
N3	5.552 [4.405; 6.997]	<0.001	2.986 [2.314; 3.854]	<0.001

DG: distal gastrectomy; TG: total gastrectomy; PG: proximal gastrectomy; U: upper; M: middle; L: lower; EGC: early gastric cancer, OR: odds ratio; 95% CI: confidence interval.