Suppression of IRE1<i>α</i> Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model

<div>Knockdown of IRE1<i>α</i> in BRL cells. (a) The representative images of BRL cells transfected with indicated lentivirus. shControl indicated the negative control shRNA and the shIRE1<i>α</i> was the shRNA targeted shIRE1<i>α</i>. Scar bar: 50 <i>μ</i>m. (b) The protein expression was detected by western blotting. GAPDH was loaded as an internal control. NC indicated BRL cells not infected with any virus. (c) Cell viability was analyzed by the method of CCK-8 after knockdown of IRE1<i>α</i> when exposed to SO for 48 h and 72 h, respectively. NG: not given (BRL cells untreated with SO). 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Gastroenterology Research and Practice

fig3

Figure 3

Figure 3: Suppression of IRE1<i>α</i> Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model 

Gastroenterology Research and Practice

Suppression of IRE1α Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model

Figure 3