Histopathologic Parameters at Diagnosis as Early Predictors of Histologic Remission along the Course of Ulcerative Colitis

Table 1

Clinical and demographic characteristics of patients with ulcerative colitis ().

Characteristics		%
Gender
Female	125	48.1
Male	135	51.9
Age at diagnosis
Before 17 years old	18	6.9
Between 17–40 years old	181	69.6
After 40 years old	61	23.5
Family history of IBD	6	2.30
Extraintestinal manifestations	145	56.0
Concomitant autoimmune disease	24	9.2
Histologic remission	56	21.5
Elevated hs-CRP (>0.36 mg/dl)	127	48.8
Positive p-ANCAs	86	33.1
Extension of the disease
Pancolitis	204	78.5
Left colitis	13	5.0
Proctosigmoiditis	43	16.5
Clinical course
Active then inactive	35	13.5
Intermittent activity	202	77.7
Chronic activity	23	8.8
Treatment
5–ASA (oral or topical)	234	91.9
Steroids	62	23.8
Azathioprine	76	29.2
Anti-TNF	8	3.1

IBD: inflammatory bowel disease; hs-CRP: high sensitive C-reactive protein; ANCAs: antineutrophil cytoplasmic antibody; 5-ASA: 5-aminosalicylic acid.