Research Article
Histopathologic Parameters at Diagnosis as Early Predictors of Histologic Remission along the Course of Ulcerative Colitis
Table 1
Clinical and demographic characteristics of patients with ulcerative colitis (
).
| Characteristics | | % |
| Gender | | | Female | 125 | 48.1 | Male | 135 | 51.9 | Age at diagnosis | | | Before 17 years old | 18 | 6.9 | Between 17–40 years old | 181 | 69.6 | After 40 years old | 61 | 23.5 | Family history of IBD | 6 | 2.30 | Extraintestinal manifestations | 145 | 56.0 | Concomitant autoimmune disease | 24 | 9.2 | Histologic remission | 56 | 21.5 | Elevated hs-CRP (>0.36 mg/dl) | 127 | 48.8 | Positive p-ANCAs | 86 | 33.1 | Extension of the disease | | | Pancolitis | 204 | 78.5 | Left colitis | 13 | 5.0 | Proctosigmoiditis | 43 | 16.5 | Clinical course | | | Active then inactive | 35 | 13.5 | Intermittent activity | 202 | 77.7 | Chronic activity | 23 | 8.8 | Treatment | | | 5–ASA (oral or topical) | 234 | 91.9 | Steroids | 62 | 23.8 | Azathioprine | 76 | 29.2 | Anti-TNF | 8 | 3.1 |
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IBD: inflammatory bowel disease; hs-CRP: high sensitive C-reactive protein; ANCAs: antineutrophil cytoplasmic antibody; 5-ASA: 5-aminosalicylic acid.
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