Histopathologic Parameters at Diagnosis as Early Predictors of Histologic Remission along the Course of Ulcerative Colitis

Table 3

Histologic characteristics of mucosal biopsies at diagnosis of ulcerative colitis in patients with documented remission through their clinical course.

	Remission		No remission
		%		%
Basal plasmacytosis	30	100	26	100
Grade 0	0	0	2	8
Grade 1	3	10	5	19
Grade 2	18	60	13	50
Grade 3	9	30	6	23
Lamina propria irregularities	30	100	26	100
Grade 0	3	10	6	23
Grade 1	5	17	9	35
Grade 2	11	37	5	19
Grade 3	11	37	6	23
Polymorphonuclear leukocytes in the lamina propria	30	100	26	100
Grade 0	2	7	8	31
Grade 1	8	27	6	23
Grade 2	11	37	10	38
Grade 3	9	30	2	8
Crypt abscesses	30	100	26	100
Grade 0	17	57	15	58
Grade 1	9	30	7	27
Grade 2	3	10	2	8
Grade 3	1	3	2	8
Crypt abscesses rupture	30	100	26	100
Grade 0	13	43	15	58
Grade 1	9	30	6	23
Grade 2	7	23	4	15
Grade 3	1	3	1	4
Glandular distortion	30	100	26	100
Grade 0	0	0	4	15
Grade 1	6	20	6	23
Grade 2	17	57	8	31
Grade 3	7	23	8	31
Glandular regenerative changes	30	100	26	100
Grade 0	2	7	5	19
Grade 1	9	30	8	31
Grade 2	16	53	10	38
Grade 3	3	10	3	12
Reduced mucin production	30	100	26	100
Grade 0	2	7	9	35
Grade 1	10	33	10	38
Grade 2	13	43	4	15
Grade 3	5	17	3	12
Eosinophils in the lamina propria	30	100	26	100
<10 per high power field	10	33	20	77
11-20 per high power field	12	40	5	19
21-30 per high power field	6	20	1	4
31-40 per high power field	2	7	0	0