Research Article

Correlation between Intraoperative Fluid Administration and Outcomes of Pancreatoduodenectomy

Table 2

Details of intraoperative characteristics, postoperative outcome (), and comparison of them among the three groups.

ParameterTotal ()Restricted group ()Standard group ()Liberal group () value (restricted vs. liberal)

IOF rate (ml/kg/hr)
Estimated blood loss (ml).304
Patients transfused in PD16 (10.60%)3(6.38%)8(10.53%)5(17.86%)
Volume of blood transfusion (ml).897
POF1 rate (ml/kg/hr).980
POF2 rate (ml/kg/hr).899
POF3 rate (ml/kg/hr).575
Postoperative length of stay (days).088
Recovery of bowel function (days).829
Drainage of POD1 (ml).286
Drainage of POD2 (ml).962
Drainage of POD3 (ml).867
Complications86 (56.95%)
POPF [26]17 (11.26%)3 (6.38%)7 (9.21%)7 (25%).035
 BL4121
 Grade B6123
 Grade C7133
Biliary fistula9 (5.96%)3 (6.38%)4 (5.26%)2 (7.14%).927
Wound infection12 (7.95%)3 (6.38%)5 (6.58%)4 (14.29%).459
Postpancreatectomy hemorrhage [28]11 (7.28%)2 (4.26%)6 (7.89%)3 (10.71%).558
Intra-abdominal infection10 (6.62%)2 (4.26%)5 (6.58%)3 (10.71%).553
Respiratory complication15 (9.93%)1 (2.13%)8 (10.53%)6 (21.43%).025
 Pulmonary infection9 (5.96%)135
 Pulmonary edema5 (3.31%)014
 Pulmonary embolus1 (0.66%)010
Delayed gastric emptying [29]5 (3.31%)1 (2.13%)2 (2.63%)2 (7.14%).456
Chylous fistula [27]3 (2.65%)02 (2.63%)1 (0.77%).485
Liver abscess2 (1.32%)1 (2.13%)1 (1.32%)0 (0).738
Others2(1.32%)01 (1.32%)1 (0.77%).738
Mortality (in-hospital)11 (7.28%)2 (4.26%)4 (5.26%)5 (17.86%).057
 POPF/intra-abdominal infection6024
 Hemorrhage3111
 Pulmonary embolus1010
 Acute renal failure1100

Abbreviations: IOF: intraoperative fluid; POF: postoperative fluid; POD: postoperative day; POPF: postoperative pancreatic fistula; BL: biochemical leak.