Increased Mast Cell Counts and Degranulation in Microscopic Colitis
Table 4
Mast cell count correlation with well-established risk factors of microscopic colitis in the study population with available relevant clinical history.
Mean highest count in lamina propria (range, number)
NSAID
No known NSAID
Collagenous colitis ()
42 (34-47, 3)n.s.
44 (29-63, 10)
Lymphocytic colitis ()
32 (21-42, 2)n.s.
30 (17-41, 9)
PPI
No known PPI
Collagenous colitis ()
43 (31-63, 3)n.s.
43 (29-62, 10)
Lymphocytic colitis ()
30 (26-33, 2)n.s.
30 (17-42, 9)
Smoking history
No known smoking history
Collagenous colitis ()
43 (34-52, 2)n.s.
43 (29-63, 11)
Lymphocytic colitis ()
33 (32-33, 2)n.s.
30 (17-42, 9)
n.s.: (Student’s -test), patients with the risk factor versus patients without. NSAID: nonsteroid anti-inflammatory drug; PPI: proton pump inhibitor (PPI).
