The Risk of Gastrointestinal Hemorrhage in Low-Dose Aspirin Users with Diabetes Mellitus: Systematic Review and Meta-Analysis

Table 1

Characteristics of studies included in the meta-analysis.

Study	Ages	Gender: male : female	Aspirin dosage (mg/day)	Aspirin duration	Cases: inclusion criteria	NOS score
Dai et al. 2014 [15]		64 : 40	100	3 months–15 years	Upper GI hemorrhage	5
Guo and Zhang 2017 [16]		80 :  56	100	3 months–14 years	GI hemorrhage	7
Kawamura et al. 2013 [17]	NR	NR	75	≥3 months	Ulcer as a mucosal deficit >5 mm in diameter	8
Li et al. 2015 [18]		118 : 102	100	≥3 months; mean months:	Gastrorrhagia and/or duodenal hemorrhage	7
Luo 2016 [19]		120 : 56	NR	≥2 months	Upper GI hemorrhage	5
Negovan et al. 2016 [20]	NR	NR	75-325	≥1 months	Gastroduodenal ulcer and/or hemorrhage	6
Quan 2015 [21]		113 : 87	NR	≥2 months	Upper GI hemorrhage	8
Zhang et al. 2016 [22]		210 : 130	≤100	≥7 days	GI hemorrhage	5

NR: not report; GI: gastrointestinal.