Effects of Serum Metabolites on the Pancreatic Transcriptome in Acute Acalculous Cholecystitis

Table 1

The top 15 nodes with the highest scores for the 4 centrality methods.

Gene symbol	Subgraph	Gene symbol	Degree	Gene symbol	Betweenness	Gene symbol	Closeness
TNF	892.7949	TNF	26	TNF	2685.522	TNF	0.100108
NOS3	523.3804	NOS3	19	NOS3	2364.1072	NOS3	0.099893
TGFB1	510.1402	TGFB1	18	TGFB1	1224.675	TGFB1	0.098101
PTGS2	325.9173	PTGS2	11	PRKG1	998.8442	PTGS2	0.096774
IFNG	260.0609	CD4	11	HSPA5	857.3439	HSPA5	0.096774
CCL2	195.3008	PRKG1	10	PRKCB	670.7727	IFNG	0.096573
CD4	194.777	IFNG	9	RYR1	591.3694	CCL2	0.096573
TLR2	172.8715	HSPA5	9	MYLK	584.6416	SGK1	0.096373
HIF1A	165.2658	TLR2	8	CACNA1S	429.81485	TLR2	0.095975
SGK1	119.9916	HIF1A	8	CD4	418.01648	HIF1A	0.095778
F3	101.6659	SGK1	8	SGK1	409.25357	PRKG1	0.095679
NPPA	100.6601	CACNA1S	8	CLU	368.7241	MYLK	0.095483
PRKG1	99.27879	CACNA1E	8	CD59	334	NPPA	0.094898
HSPA5	96.47914	CCL2	7	ADCY5	332	EDNRB	0.094608
TIMP1	79.86854	RYR1	7	MYH11	332	PRKCB	0.094608