p53 Immunohistochemistry Patterns Are Surrogate Biomarkers for TP53 Mutations in Gastrointestinal Neuroendocrine Neoplasms

Figure 1

The “lollipop” plot generated by the MutationMapper tool of cBioPortal [31, 32] shows the open box of TP53 gene, as well as the frequency and position of TP53 mutations in GI-NENs in our study. AD: transactivation domain; DBD: DNA binding domain; MD: tetramerization domain.