Research Article

p53 Immunohistochemistry Patterns Are Surrogate Biomarkers for TP53 Mutations in Gastrointestinal Neuroendocrine Neoplasms

Table 4

Comparison of p53 IHC staining patterns among NET and NEC cases.

IHC patternsNETs, no. (%)NECs, no. (%) value

Pattern A2 (5.7)11 (19.3)<0.001
Pattern B31 (88.6)4 (7.0)
Pattern C106 (10.5)
Pattern C22 (5.7)36 (63.2)