MiR-490-5p Restrains Progression of Gastric cancer through DTL Repression

Figure 5

MiR-490-5p constrains cell proliferation, migration, invasion, while facilitates cell apoptosis of GC through DTL repression. A: MiR-490-5p mimic led to decrease of DTL protein level in MGC-803 cells; B: The cell viability was assessed with CCK-8 assay in miR-NC + vector, miR-490-5p mimic+vector, and miR-490-5p mimic+DTL groups; C-D: Cell (C) migration and (D) invasion were measured with Transwell assay (100 ×); E-F: The (E) cell cycle and (F) apoptosis were assayed with flow cytometry; p <0.05, p <0.01.

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