Research Article

Clinical Outcomes of Ileostomy Closure before Adjuvant Chemotherapy after Rectal Cancer Surgery: An Observational Study from a Chinese Center

Table 1

Demographics and clinicopathologic characteristics of the study groups.

Group I ()Group II ()Group III () value

Sex
 Male16 (66.7%)41 (77.4%)32 (58.2%)0.104
 Female8 (33.3%)12 (22.6%)23 (41.18%)
Age (years)0.304
BMI (kg/m2)0.073
Comorbidity
 Cardiovascular diseases2 (8.3%)8 (15.1%)12 (21.8%)0.310
 Diabetes0 (0.0%)6 (4.5%)3 (2.3%)0.165
 Pulmonary diseases1 (4.2%)1 (1.9%)1 (1.8%)0.789
 Renal diseases0 (0.0%)1 (1.9%)2 (3.6%)0.590
ASA class0.961
 I3 (12.5%)5 (9.4%)4 (7.3%)
 II19 (79.2%)44 (83.0%)47 (85.5%)
 III2 (8.3%)4 (7.5%)4 (7.3%)
Type of surgery0.994
 Laparoscopic23 (95.8%)51 (96.2%)53 (96.4%)
 Conversion to open1 (4.2%)2 (3.8%)2 (3.6%)
cTNM stage0.706
 I1 (4.2%)5 (5.7%)18 (7.3%)
 II5 (20.8%)17 (32.1%)33 (21.8%)
 III18 (75.0%)33 (62.3%)39 (70.9%)
ypTNM stage0.471
 01 (4.2%)0 (0.0%)1 (1.8%)
 I2 (8.3%)4 (7.5%)9 (16.4%)
 II12 (50.0%)25 (47.2%)28 (50.9%)
 III9 (37.5%)24 (45.3%)17 (30.9%)
Neoadjuvant CRT10 (41.7%)19 (35.8%)25 (45.5%)0.595
Tumor location (cm)0.698
 3-59 (37.5%)22 (41.5%)16 (29.1%)0.597
 6-109 (37.5%)23 (43.4%)27 (49.1%)
 11-156 (25.0%)8 (15.1%)12 (21.8%)

Values are presented as the or number of patients (%). Measured before ileostomy closure. Pathological stage according to UICC. Tumor lower border from the anal verge. BMI: body mass index; ASA: American Society of Anesthesiologists; UICC: Union Internationale Contre le Cancer; CRT: chemoradiotherapy.