Prediction and Risk Factors for Prognosis of Cirrhotic Patients with Hepatic Encephalopathy

Table 2

Diagnostic accuracies of Child-Pugh, ALBI, MELD, MELD-Na, and NLR scores.

Prognostic model	Area under the ROC curve	Criterion value	Sensitivity	Specificity	Positive LR	Negative LR	Positive PV	Negative PV	value
The whole patients
Child-Pugh	0.681 (95% CI: 0.626-0.733)	10.0	79.7	46.3	1.5	0.4	28.3	89.5	<0.0001
ALBI	0.615 (95% CI: 0.558-0.670)	-1.3	76.6	44.2	1.4	0.5	26.8	87.6	0.0030
MELD	0.630 (95% CI: 0.573-0.684)	19.0	76.6	52.5	1.6	0.5	30.1	89.4	0.0005
MELD-Na	0.640 (95% CI: 0.583-0.694)	20.0	81.3	45.8	1.5	0.4	28.6	90.2	0.0002
NLR	0.664 (95% CI: 0.608-0.717)	7.2	53.1	79.2	2.6	0.6	40.5	86.4	<0.0001
ACLF subgroup
Child-Pugh	0.621 (95% CI: 0.533-0.703)	11.0	76.3	41.1	1.3	0.6	34.1	81.2	0.0165
ALBI	0.578 (95% CI: 0.489-0.663)	-1.3	89.5	28.4	1.3	0.4	33.3	87.1	0.1487
MELD	0.531 (95% CI: 0.443-0.618)	27.0	65.8	51.6	1.4	0.7	35.2	79.0	0.5870
MELD-Na	0.500 (95% CI: 0.412-0.588)	27.0	52.6	59.0	1.3	0.8	33.9	75.7	0.9963
NLR	0.701 (95% CI: 0.616-0.778)	7.2	60.5	82.1	3.4	0.5	57.5	83.9	0.0003

Abbreviations: ACLF: acute-on-chronic liver failure; ALBI: albumin to bilirubin; CI: confidence interval; HE: hepatic encephalopathy; LR: likelihood ratio; MELD: model for end-stage liver diseases; MELD-Na: model for end-stage liver diseases-sodium; NLR: neutrophil to lymphocyte ratio; PV: predictive value; ROC: receiver operating characteristic. Note: value < 0.05.