Prognostic Value of Inflammatory and Tumour Markers in Small-Duct Subtype Intrahepatic Cholangiocarcinoma after Curative-Intent Resection

Table 1

Univariate analysis of prognostic factors for ICC in the training cohort.

Variables	DFS			OS
	HR	95% CI	value	HR	95% CI	value
Platelet (10^9/L)	1.450	0.758-2.776	0.262	0.750	0.367-1.535	0.431
(<165 vs. ≥165)
Neutrophil (10^9/L)	2.183	1.331-3.581	0.002	2.441	1.311-4.544	0.005
(<4.15 vs. ≥4.15)
Lymphocyte (10^9/L)	0.600	0.368-0.978	0.041	0.564	0.305-1.043	0.068
(<1.60 vs. ≥1.60)
Monocyte (10^9/L)	1.697	0.970-2.969	0.064	2.307	1.162-4.581	0.017
(<0.54 vs. ≥0.54)
NLR	2.081	1.156-3.747	0.015	2.698	1.338-5.442	0.006
(<3.00 vs. ≥3.00)
LMR	0.454	0.215-0.960	0.039	0.275	0.110-0.684	0.006
(<2.70 vs. ≥2.70)
PLR	1.851	0.987-3.474	0.055	0.910	0.456-1.817	0.789
(<90.0 vs. ≥90.0)
CEA (ug/L)	2.555	1.518-4.299	≤0.001	2.193	1.120-4.293	0.022
(<4.50 vs. ≥4.50)
CA19-9 (U/ml)	2.974	1.791-4.936	≤0.001	2.775	1.464-5.262	0.002
(<76.0 vs. ≥76.0)
CA242 (IU/ml)	2.976	1.688-5.247	≤0.001	2.511	1.235-5.106	0.011
(<30.0 vs. ≥30.0)
Ferritin (ug/L)	2.495	1.372-4.538	0.003	3.761	1.650-8.572	0.002
(<150.0 vs. ≥150.0)
PII	2.685	1.498-4.812	0.001	3.161	1.628-6.138	0.001
(<1.50 vs. ≥1.50)