Research Article
Postoperative Ratio of C-Reactive Protein to Albumin as a Predictive Marker in Patients with Crohn’s Disease Undergoing Bowel Resection
Table 1
Characteristic of participants and univariate analysis of risk factors associated with postoperative complications.
| | Characteristics | All (534) | With complications (172) | Without complications (362) | value |
| | Age | | | | 0.928 | | Men | 375 (70.2) | 119 (69.2) | 256 (70.7) | 0.717 | | BMI | | | | <0.001 | | Preoperative Hb | | | | 0.054 | | Preoperative ALB | | | | 0.001 | | Postoperative CRP | | | | <0.001 | | Postoperative CAR | | | | <0.001 | | Preoperative CRP | | | | <0.001 | | Preoperative ESR | | | | 0.086 | | Preoperative WBC | | | | 0.120 | | Preoperative RBC | | | | 0.133 | | Preoperative PLT | | | | 0.572 | | Preoperative lymphocyte | | | | 0.176 | | Current smoking | 20 (3.7) | 7 (4.1) | 13 (3.6) | 0.785 | | Disease duration before surgery | | | | 0.457 | | Preoperative optimization | | Exclusive enteral nutrition | 158 (29.6) | 37 (21.5) | 121 (33.4) | 0.005 | | Total parenteral nutrition | 67 (12.5) | 17 (9.9) | 50 (13.8) | 0.200 | | Abscesses drainage | 65 (12.2) | 20 (11.6) | 45 (12.4) | 0.791 | | Montreal classification | | Age, y | | | | | | A1 (≤16) | 3 (0.6) | 2 (1.2) | 1 (0.3) | 0.224 | | A2 (17-40) | 396 (74.2) | 127 (73.8) | 269 (74.3) | 0.907 | | A3 (>40) | 135 (25.3) | 43 (25.0) | 92 (25.4) | 0.918 | | Location | | L1 (ileal) | 147 (27.5) | 55 (32.0) | 92 (25.4) | 0.113 | | L2 (colonic) | 76 (14.2) | 24 (14.0) | 52 (14.4) | 0.899 | | L3 (ileocolonic) | 303 (56.7) | 104 (60.5) | 199 (55.0) | 0.231 | | L4 (upper gastrointestinal) | 44 (8.2) | 15 (8.7) | 29 (8.0) | 0.780 | | Behavior | | B1 (inflammatory/failure of medical therapy) | 35 (6.6) | 9 (5.2) | 26 (7.2) | 0.395 | | B2 (stricturing) | 348 (65.2) | 109 (63.3) | 239 (66.0) | 0.418 | | B3 (penetrating) | 199 (37.3) | 72 (41.9) | 127 (35.1) | 0.130 | | Perianal disease | 150 (28.1) | 43 (25.0) | 107 (29.6) | 0.273 | | Operative time | | | | <0.001 | | 45 (8.4) | 14 (8.1) | 31 (8.6) | 0.869 | | First time operated | 299 (56.0) | 83 (48.3) | 216 (59.7) | 0.013 | | Laparoscopic surgery | 264 (49.4) | 50 (29.0) | 214 (59.1) | <0.001 | | Conversion | 101 (18.9) | 36 (20.9) | 65 (18.0) | 0.412 | | Estimated blood loss | | | | <0.001 | | Preoperative treatment | | Azathioprine | 111 (20.8) | 33 (19.2) | 78 (21.5) | 0.530 | | Infliximab | 115 (21.5) | 43 (25.0) | 72 (19.9) | 0.179 | | 5-ASA | 144 (27.0) | 45 (26.2) | 99 (27.3) | 0.773 | | Corticosteroids | 25 (4.7) | 5 (2.9) | 20 (5.5) | 0.181 | | Others | 117 (21.9) | 42 (24.4) | 75 (20.7) | 0.334 |
|
|
BMI: body mass index; Hb: haemoglobin; ALB: albumin; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; WBC: white blood cell; RBC: red blood cell; PLT: platelet; CAR: the CRP/ALB ratio.
|
