Research Article
Clinical Features of False-Negative Early Gastric Cancers: A Retrospective Study of Endoscopic Submucosal Dissection Cases
Table 1
Clinical characteristics in the initially detected and false-negative EGCs.
| | Initially detected EGCs () | False-negative EGCs () | value |
| | Age (years) | 71 | [61–79] | 72 | [63–79] | 0.61 | | Men | 73 | (73.0%) | 86 | (72.3%) | 0.90 | | Previous ESD/EMR | 1 | (1.0%) | 34 | (28.6%) | <0.01 | | Symptomatic | 30 | (30.0%) | 12 | (10.1%) | <0.01 | | Atrophic gastritis | | | | | 0.38 | | Opened type | 87 | (87.0%) | 108 | (90.8%) | | | None or closed type | 13 | (13.0%) | 11 | (9.2%) | | | Helicobacter pylori status | | | | | <0.01 | | Currently infected | 75 | (75.0%) | 50 | (42.0%) | | | Past infected | 18 | (18.0%) | 64 | (53.8%) | | | Uninfected | 7 | (7.0%) | 5 | (4.2%) | | | Endoscopist | | | | | 0.59 | | Experienced | 69 | (69.0%) | 86 | (72.3%) | | | Trainee | 31 | (31.0%) | 33 | (27.7%) | | | Purpose | | | | | <0.01 | | Screening | 78 | (78.0%) | 43 | (36.1%) | | | Surveillance | 1 | (1.0%) | 37 | (31.1%) | | | Annual medical checkup | 21 | (21.0%) | 39 | (32.8%) | | | Tumor size (mm) | 15 | [9–23] | 9 | [5–13] | <0.01 | | Depth | | | | | 0.09 | | M | 90 | (90.0%) | 115 | (96.6%) | | | sm1 | 2 | (2.0%) | 0 | (0%) | | | sm2 or deeper | 8 | (8.0%) | 4 | (3.4%) | | | Pathological differentiation | | | | | 0.19 | | Well or moderate | 83 | (83.0%) | 106 | (89.1%) | | | Poorly | 17 | (17.0%) | 13 | (10.9%) | | | Location | | | | | 0.82 | | Upper | 13 | (13.0%) | 19 | (16.0%) | | | Middle | 33 | (33.0%) | 37 | (31.1%) | | | Lower | 54 | (54.0%) | 63 | (52.9%) | | | Circumference | | | | | 0.51 | | Anterior wall | 23 | (23.0%) | 22 | (18.5%) | | | Posterior wall | 25 | (25.0%) | 40 | (33.6%) | | | Lesser curvature | 35 | (35.0%) | 36 | (30.3%) | | | Greater curvature | 17 | (17.0%) | 21 | (17.7%) | | | Color | | | | | <0.01 | | Reddish | 55 | (55.0%) | 71 | (59.7%) | | | Discolored | 40 | (40.0%) | 29 | (24.4%) | | | Normal | 5 | (5.0%) | 19 | (16.0%) | | | Tumor morphology | | | | | 0.33 | | Elevated | 33 | (33.0%) | 29 | (24.4%) | | | Flat | 9 | (9.0%) | 11 | (9.2%) | | | Depressed | 57 | (58.0%) | 79 | (66.4%) | | | Erosion | | | | | 0.86 | | Present | 45 | (45.0%) | 55 | (46.2%) | | | Absent | 55 | (55.0%) | 64 | (53.8%) | | | Gastritis-like appearance | | | | | <0.01 | | Present | 15 | (15.0%) | 42 | (35.3%) | | | Absent | 85 | (85.0%) | 77 | (64.7%) | | | Spontaneous bleeding | | | | | 0.72 | | Present | 16 | (16.0%) | 17 | (14.3%) | | | Absent | 84 | (84.0%) | 102 | (85.7%) | |
|
|
Data are presented as median (IQR) or (%). EGC: early gastric cancer; ESD: endoscopic submucosal dissection; EMR: endoscopic mucosal resection. |
