Serum Exosomes Derived from Irritable Bowel Syndrome Patient Increase Cell Permeability via Regulating miR-148b-5p/RGS2 Signaling in Human Colonic Epithelium Cells

Figure 5

RGS2 overexpression disrupts the effects of miR-148b-5p overexpression on permeability of HT-29 cells. (a) TEER value of the HT-29 cells cotransfected with miR-148b-5p mimic and oeRGS2 or oeNC. (b) FITC-Dextran influx of the HT-29 cells cotransfected with miR-148b-5p mimic and oeRGS2 or oeNC. (c) RGS2 protein levels of the HT-29 cells with different treatments. HT-29 cells are cotransfected with miR-148b-5p mimic and oeRGS2 or oeNC. value < 0.001 vs. control, ^!!! value < 0.001 vs. oeNC.

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