Clinical Significance of Lymph Node Micrometastasis in pN0 Gastric Cancer Patients
Table 1
Clinicopathological factors of the patients associated with LNMM.
Clinicopathological factors, (%)
LNMM
value
Yes
No
Gender
0.059
Male
56 (77.8)
66 (66.0)
Female
16 (22.2)
34 (34.0)
Age
0.749
≤60
40 (55.6)
58 (58.0
≥60
32 (44.4)
42 (42.0)
Tumor size (cm)
0.031
≤2
6 (8.3)
25 (25.0)
2~5
37 (51.4)
42 (42.0)
≥5
29 (40.3)
33 (33.0)
Tumor differentiation
0.032
High or moderate differentiation
13 (18.1)
34 (34.0)
Low differentiation
59 (81.9)
66 (66.0)
The depth of tumor invasion
0.001
T1
2 (2.8)
17 (17.0)
T2
8 (11.1)
18 (18.0)
T3
46 (63.9)
55 (55.0)
T4
16 (22.2)
10 (10.0)
Surgical approach
0.636
Total gastrectomy
49 (68.1)
70 (70.0)
Distal gastrectomy
23 (31.9)
30 (30.0)
General type
0.181
Topical type
23 (31.9)
42 (42.0)
Infiltrative type
49 (68.1)
58 (58.0)
Lauren classification
0.034
Diffusive type
51 (70.8)
53 (53.0)
Intestinal type
21 (29.2)
47 (47.0)
TNM staging
0.005
IA
2 (2.8)
17 (17.0)
IB
8 (11.1)
18 (18.0)
IIA
46 (63.9)
55 (55.0)
IIB
11 (15.3)
8 (8.0)
III
5 (6.9)
2 (2.0)
Lymphatic infiltration
0.043
Yes
47 (65.3)
54 (54.0)
No.
25 (34.7)
46 (46.0)
Neural invasion
0.067
Yes
36 (50.0)
46 (46.0)
No
36 (50.0)
54 (54.0)
: number; LNMM: lymph node micrometastasis; TNM: tumor node metastasis; value was derived from the univariable association analyses between each characteristic; .