The Diagnostic Value of Serum Gastrin-17 and Pepsinogen for Gastric Cancer Screening in Eastern China

Figure 1

Determination of the cutoff values of G-17, PGII, and PGR and diagnostic value. (a) ROC curve of NAG and CAG. G-17: AUC is 0.555 (CI 0.512-0.598), YI is 0.101, and cutoff value is 9.25; PGII: AUC is 0.561 (CI 0.518-0.604), YI is 0.120, and cutoff value is 7.06; PGR: AUC is 0.571 (CI 0.528-0.614), YI is 0.135, and cutoff value is 12.07. (b) ROC curve of CG and IN. G-17 : AUC is 0.722 (CI 0.642-0.801), YI is 0.379, and cutoff value is 3.86; PGII: AUC is 0.697 (CI 0.611-0.783), YI is 0.362, and cutoff value is 11.92; PGR: AUC is 0.687 (CI 0.604-0.771), YI is 0.328, and cutoff value is 8.26. (c) ROC curve of CG and GC. G-17: AUC is 0.753 (CI 0.684-0.821), YI is 0.403, and cutoff value is 3.89; PGII: AUC is 0.717 (CI 0.642-0.793), YI is 0.342, and cutoff value is 9.16; PGR: AUC is 0.729 (CI 0.650-0.807), YI is 0.357, and cutoff value is 14.14. AUC: area under the receiver operating characteristic curve; YI: Youden index; CI: confidence interval.

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