Study of the Mechanism by Which Curcumin Cooperates with Sestrin2 to Inhibit the Growth of Pancreatic Cancer

Figure 2

Upregulation of sestrin2 can inhibit the abilities of proliferation and migration of pancreatic cancer cells. The changes in the migration ability of the PANC-1 cell-sestrin2 overexpression group (sestrin2+) and sestrin2 knockdown group (sestrin2-) (a); the distance change of the migration is presented in the form of a histogram (b); data are represented as the (). compared with control groups, compared with control groups. The changes in the migration ability of the CFPAC-1-sestrin2 overexpression group (sestrin2+) and sestrin2 knockdown group (sestrin2-) (c); the distance change of the migration is presented in the form of a histogram (d); data are represented as the (). compared with control groups; the real-time cell analysis technology was utilized to examine the ability of proliferation of PANC-1 and CFPAC-1 cells after being infected with sestrin2 overexpression/knockdown lentivirus (e, f).

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