A Comprehensive Review of Infectious Granulomatous Diseases of the Gastrointestinal Tract

Figure 1

Histological features of intestinal tuberculosis (ITB) and Crohn’s disease (CD) discovered in endoscopic biopsy specimens. ITB commonly features several large, confluent caseating granulomas (a), with central necrosis (b) and giant cells (e). CD features relatively few, small granulomas (c). Large granulomas in CD are rare, and if present, they are poorly organized (d). Basal plasmacytosis can be seen in CD (f). (Images obtained with permission from Ye et al. [20].

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