Clinical Characteristics and Manifestations of Fungal Esophagitis: A Single-Center Experience in South China

Table 3

Univariate and multivariate regression analyses of the factors related to FE.

Variables	Univariate analysis		Multivariate analysis
	Odds ratio (95% CI)	value	Odds ratio (95% CI)	value
Sex, male	1.755 (1.054, 2.921)	0.031
Age group				0.018
≤30	0.184 (0.078, 0.436)	0.000	0.203 (0.077, 0.535)	0.001
31~40	0.385 (0.183, 0.810)	0.012	0.410 (0.177, 0.953)	0.038
41~50	0.407 (0.198, 0.837)	0.015	0.388 (0.173, 0.870)	0.022
51~60	0.446 (0.206, 0.966)	0.041	0.354 (0.143, 0.873)	0.024
>60	1 (ref)
Symptom of globus sensation	4.835 (2.239, 10.441)	0.000	7.507 (3.156, 17.860)	0.000
Symptom of epigastric pain	2.055 (1.163, 3.633)	0.013
Comorbidity of EP	4.940 (1.249, 19.529)	0.023	8.732 (2.006, 38.013)	0.004
Comorbidity of diabetes	1.935 (0.822, 4.554)	0.130
Comorbidity of malignancy	3.614 (1.575, 8.291)	0.002	4.031 (1.562, 10.407)	0.004
History of IS use	9.783 (2.072, 46.180)	0.004	6.525 (1.089, 39.105)	0.040
History of antibiotic use	2.247 (1.230, 4.105)	0.008	2.178 (1.078, 4.400)	0.030
Smoking	2.548 (1.500, 4.325)	0.001	3.017 (1.645,5.533)	0.000

EP: esophageal polyps; IS: immunosuppressant.