Clinical Features, Endoscopic Findings, and Predictive Factors for Mortality in Tissue-Invasive Gastrointestinal Cytomegalovirus Disease between Immunocompetent and Immunocompromised Patients
Table 2
The locations and endoscopic finding of TI-GI CMV disease between immunocompromised and immunocompetent patients.
Characteristics
Overall ()
Immunocompromised ()
Immunocompetent ()
value
Presenting symptoms
Symptom onset in days Median (IQR)
7 (1-84)
14 (1-84)
2 (1-21)
0.018
Gastrointestinal bleeding
78 (36.6)
36 (29.0)
42 (47.2)
0.010
Abdominal pain
45 (21.1)
32 (25.8)
13 (14.6)
0.071
Diarrhea
120 (56.3)
70 (56.5)
50 (56.2)
1.000
Odynophagia or dysphagia
22 (10.3)
18 (14.5)
4 (4.5)
0.032
Nausea/vomiting
7 (3.3)
5 (4.0)
2 (2.2)
0.702
Significant weight loss
25 (11.7)
22 (17.7)
3 (3.4)
0.003
Fever
55 (25.8)
29 (23.4)
26 (29.2)
0.424
Sites of involvement
Esophagus
23 (10.8)
18 (14.5)
5 (5.6)
0.046
Stomach
11 (5.2)
7 (5.6)
4 (4.5)
0.765
Small bowel
27 (12.7)
10 (8.1)
17 (19.1)
0.029
Colon and rectum
130 (61.0)
71 (57.3)
59 (66.3)
0.234
Diffuse GI lesions (≥2 sites)
22 (10.3)
18 (14.5)
4 (4.5)
0.032
Extra-GI involvement
8 (3.8)
8 (6.5)
0 (0)
0.022
Endoscopic findings
Erythematous, edematous
21 (9.9)
18 (14.5)
3 (3.4)
0.021
Mucosal hemorrhage
14 (6.6)
5 (4.0)
9 (10.1)
0.137
Erosion
26 (12.2)
13 (10.5)
13 (14.6)
0.487
Ulcer
139 (65.3)
81 (65.3)
58 (65.2)
1.000
Mass
9 (4.2)
6 (4.8)
3 (3.4)
0.738
Pseudomembranous
5 (2.3)
1 (0.8)
4 (4.5)
0.163
Data are presented as number (percentage) unless indicated otherwise. Abbreviations: GI: gastrointestinal; IQR: interquartile range.
