Research Article

Usefulness of Measuring Thiopurine Metabolites in Children with Inflammatory Bowel Disease and Autoimmunological Hepatitis, Treated with Azathioprine

Table 1

Background information about the group receiving azathioprine.

CharacteristicsValues

Total number of patients61
Females (percent)27 (44%)
Age ()
Crohn’s disease (CD)31 (50%)
Ulcerative colitis (UC)16 (26%)
Autoimmune hepatitis (AIH)14 (23%)
Weight SDS ()
CD
UC
AIH
Height SDS ()
CD
UC
AIH
BMI SDS ()
CD
UC
AIH
Premonitoring azathioprine dose mg/kg ()
CD
UC
AIH
Postmonitoring azathioprine dose mg/kg ()
CD
UC
AIH
6-TGN ()
CD
UC
AIH
6-MMP ()
CD
UC
AIH
Disease activity:
Remission/mild form of IBD32 (68%)
Moderate form of IBD10 (21%)
Severe form of IBD5 (11%)
Remission of AIH14 (100%)

SD: standard deviation; 6-MMP: 6-methylmercaptopurine; 6-TGN: 6-thioguanine; IBD: inflammatory bowel disease; AIH: autoimmunological hepatitis; CD: Crohn’s disease; UC: ulcerative colitis.