Characterization of Desmoglein 3 (DSG3) as a Sensitive and Specific Marker for Esophageal Squamous Cell Carcinoma

Table 3

Percentage of positive esophageal squamous cell carcinoma components (≥5% immunoreactive cells).

	P40	CK5/6	DSG3
SCC WD components	95% (19/20)	100% (20/20)	100% (20/20)
SCC MD components	100% (26/26)	100% (25/25)	100% (26/26)
SCC PD components	100% (17/17)	100% (17/17)	100% (17/17)
SCC all components	98% (62/63)	100% (62/62)	100% (63/63)

Abbreviations: SCC: squamous cell carcinoma; WD: well-differentiated; MD: moderately differentiated; PD: poorly differentiated. CK5/6 immunostain is not available in one SCC case with MD component only.