Exploring Different Effects of Exclusive Enteral Nutrition (EEN) and Corticosteroids on the Gut Microbiome in Crohn’s Disease Based on a Three-Stage Strategy

Table 2

Clinical outcome of corticosteroids and EEN therapy.

	Subject	Before ( =8)	After ( =8)	value
Corticosteroids ( =8)	CDAI	274.81 ± 92.14	98.63 ± 28.05	<0.001
	ES (mm/h)	37.70 ± 3.23	18.69 ± 3.88	<0.001
	CRP (mg/L)	35.79 ± 15.89	12.49 ± 3.80	0.001
	HB (g/L)	102.45 ± 14.23	117.50 ± 10.85	0.032
	ALB (mg/L)	31.00 ± 4.38	33.19 ± 2.36	0.234
	W (kg)	47.23 ± 10.21	48.14 ± 10.99	0.866
	SMM (kg)	21.68 ± 6.07	22.00 ± 6.19	0.920
EEN ( =8)	CDAI	253.86 ± 71.69	103.71 ± 44.13	<0.001
	ESR (mm/h)	35.94 ± 12.25	19.0 ± 4.69	0.003
	CRP (mg/L)	33.55 ± 14.28	13.88 ± 5.96	0.003
	HB (g/L)	108.87 ± 12.85	128.36 ± 9.91	0.004
	ALB (mg/L)	30.86 ± 3.05	37.94 ± 3.40	0.001
	W (kg)	47.81 ± 8.23	49.19 ± 7.69	0.735
	SMM (kg)	21.63 ± 5.61	23.01 ± 5.07	0.618

Abbreviations: CDAI: Crohn’s disease activity index; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; HB: hemoglobin; ALB: albumin; SM: skeletal muscle; before: before treatment; after: after treatment; W: weight.