Research Article

Sedation Is Associated with Higher Polyp and Adenoma Detection Rates during Colonoscopy: A Retrospective Cohort Study

Table 1

Characteristics of the patients.

VariableAll patients ()No-sedation ()Sedation ()-value

Age (years)<0.001
Sex
 Male6547 (51.5%)1910 (55.1%)4637 (50.1%)<0.001
 Female6169 (48.5%)1556 (44.9%)4613 (49.9%)
Year of colonoscopy
 20173356 (26.4%)1040 (30%)2316 (25%)<0.001
 20184157 (32.7%)1225 (35.3%)2932 (31.7%)
 20195010 (39.4%)1157 (33.4%)3853 (41.7%)
 2020193 (1.5%)44 (1.3%)149 (1.6%)
Time of colonoscopy
 AM (8–12)4282 (33.7%)42 (1.2%)4240 (45.8%)<0.001
 PM (12–17)8434 (66.3%)3424 (98.8%)5010 (54.2%)
Reason for colonoscopy
 Unknown57 (0.4%)4 (0.1%)53 (0.6%)<0.001
 Screening2188 (17.2%)344 (9.9%)1844 (19.9%)
 Diagnosis8886 (69.9%)2685 (77.5%)6201 (67.0%)
 Others1585 (12.5%)433 (12.5%)1152 (12.5%)
Endoscopist factors
 Volumea < 3001372 (10.8%)90 (2.6%)1282 (13.9%)<0.001
 300 ≤ volume < 7007218 (56.8%)1980 (57.1%)5238 (56.6%)
 700 ≤ volume4126 (32.4%)1396 (40.3%)2730 (29.5%)
 Experienceb < 31641 (12.9%)696 (20.1%)945 (10.2%)
 3 ≤ experience < 77105 (55.9%)2327 (67.1%)4778 (51.7%)
 7 ≤ experience3970 (31.2%)443 (12.8%)3527 (38.1%)
Score of BBPS<0.001
Total number of biopsies<0.001
Number of polyps per colonoscopy<0.001
Treatment
 No treatment5659 (44.5%)1767 (51%)3892 (42.1%)<0.001
 Deal with biopsy forceps5170 (40.7%)1385 (40%)3785 (40.9%)
 Polypectomy with other methodc1887 (14.8%)314 (9.1%)1573 (17%)
Withdrawal time (minutes)<0.058
 No treatment
 Deal with biopsy forceps
 Polypectomy with other method
Group of withdrawal time (minutes)
 <63250 (25.6%)786 (22.7%)2464 (26.6%)<0.001
 6–12n7202 (56.6%)2060 (59.4%)5142 (55.6%)
 >122264 (17.8%)620 (17.9%)1644 (17.8%)

BBPS: the Boston Bowel Preparation Scale score.
aVolume: the number of colonoscopies performed by endoscopists annually.
bExperience: years since completing colonoscopy independently.
cIncluding polypectomy with snare wire, argon plasma coagulation, or electrocoagulation.