EMP1 as a Potential Biomarker in Liver Fibrosis: A Bioinformatics Analysis

Figure 5

EMP1 expression positively correlated with fibrotic-related genes in liver. Significant positive correlations of EMP1 expression with fibrotic-related genes including TGFB1 (a), COL1A2 (b), MMP9 (c), and VIM (d), according to the expression profile from GTEx normal liver RNA-sequencing matrix in GEPIA2. (e) Barplot of cell clusters (y-axis) and cell types (x-axis) where the gene is expressed. Expression enrichment of EMP1 in different cell types from 363 scRNA-seq samples and 1487 cell clusters according to PanglaoDB. COL1A2, collagen type i alpha 2 chain; EMP1, epithelial membrane protein 1; GEPIA2, Gene Expression Profiling Interactive Analysis; GTEx, Genotype-Tissue Expression; MMP9, matrix metallopeptidase 9; scRNA-seq, single-cell RNA sequencing; TGFB1, transforming growth factor beta 1; VIM, vimentin.

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