Gastroenterology Research and Practice

Translational Research in Colorectal Cancer: Current Status and Future Perspectives of Multimodal Treatment Approach

Publishing date
01 Sep 2018
Submission deadline
11 May 2018

Lead Editor

1“San Matteo degli Infermi” Hospital, Spoleto, Italy

2Università della Campania “Luigi Vanvitelli”, Naples, Italy

3Imperial College London, London, UK

4Queen Alexandra Hospital, Portsmouth, UK

5University Hospital La Fe, Valencia, Spain

Translational Research in Colorectal Cancer: Current Status and Future Perspectives of Multimodal Treatment Approach


Research in the last decade has resulted in numerous advances in our understanding of the underlying mechanisms of colorectal malignancy and progression. The need for colorectal cancer treatments to account for these complex biological, genetic, and epigenetic factors is now widely accepted and most treatment guidelines account for these variables.

Furthermore, one of the main milestones in the treatment of colorectal cancer, which has overall resulted in the five-year survival improvement, is the multimodal treatment approach: it imposes the close interdisciplinary cooperation between colorectal surgeons, oncologists, radiologists, and radiotherapists.

Therefore, we invite researchers to contribute to this special issue with high-quality original papers, as well as review articles, focusing on current status and future perspectives of multimodal treatment approach in the field of colorectal cancer.

Potential topics include but are not limited to the following:

  • Molecular biology and genetic and epigenetic factors which could help in selecting patients for treatment and predicting prognosis
  • Noninvasive molecular biomarkers for predicting and monitoring response to treatment
  • Translational and clinical trials focused on novel treatment alternatives
  • Systematic reviews (if appropriate) summarizing the available data from the literature
  • Multidisciplinary management of colorectal cancer, including locally advanced and recurrent malignancies and synchronous and metachronous metastatic diseases: topics can range from new minimally invasive approaches (e.g., transanal TME, robotic surgery) to surgical debulking and intraperitoneal chemotherapy, targeted therapy, neoadjuvant regimens, and experimental treatments
  • Evaluation of efficacy, side effects, and cost-effectiveness of the procedures
  • Special consideration given to studies focused on patient-reported outcome measures and health-related quality of life in the settings of advanced cancers, treatment counseling, and genetic and biomolecular testing for colorectal malignancies


  • Special Issue
  • - Volume 2019
  • - Article ID 2010259
  • - Editorial

Translational Research in Colorectal Cancer: Current Status and Future Perspectives of Multimodal Treatment Approach

Luigi Marano | Gianluca Pellino | ... | Matteo Frasson
  • Special Issue
  • - Volume 2019
  • - Article ID 7476023
  • - Review Article

Same-Day Regimen as an Alternative to Split Preparation for Colonoscopy: A Systematic Review with Meta-Analysis

Cristina Bucci | Fabiana Zingone | ... | Riccardo Marmo
  • Special Issue
  • - Volume 2018
  • - Article ID 7153685
  • - Research Article

Different Anatomical Subsites of Colon Cancer and Mortality: A Population-Based Study

Xing-kang He | Wenrui Wu | ... | Jianmin Si
  • Special Issue
  • - Volume 2018
  • - Article ID 7968149
  • - Research Article

Cyclooxygenase-2 Expression Is a Predictive Marker for Late Recurrence in Colorectal Cancer

Sung Hoo Kim | Byung Kyu Ahn | ... | Kang Hong Lee
  • Special Issue
  • - Volume 2018
  • - Article ID 2397863
  • - Review Article

Noninvasive Biomarkers of Colorectal Cancer: Role in Diagnosis and Personalised Treatment Perspectives

Gianluca Pellino | Gaetano Gallo | ... | Francesco Selvaggi
  • Special Issue
  • - Volume 2018
  • - Article ID 5284754
  • - Research Article

Colonic Mucosal Microbiota in Colorectal Cancer: A Single-Center Metagenomic Study in Saudi Arabia

Ahmed O. Alomair | Ibrahim Masoodi | ... | Ali S. Alshanqeeti
Gastroenterology Research and Practice
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Acceptance rate5%
Submission to final decision98 days
Acceptance to publication22 days
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Impact Factor2.0
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