Gastroenterology Research and Practice

Pancreatic Cancer


Publishing date
12 Sep 2014
Status
Published
Submission deadline
25 Apr 2014

Lead Editor

1Department of Surgery, Division of Surgical Pathology, University of Pisa, Via Paradisa 2, Univeristy Hospital, 56124 Pisa, Italy

2Karolinska Istitute, Division of Surgery, Solna, Sweden

3Department of Gastroenterology & Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands

4Department of Gastroenterology and Alimentary Tract Surgery, University Hospital of Tampere, Tampere, Finland


Pancreatic Cancer

Description

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death, with only 3% of patients alive 5 years after diagnosis. The main reasons for this grim prognosis include early metastatic spread, high local recurrence rate, and multifactorial resistance to treatments. In 85% of patients, PDAC is detected at advanced stages, characterized by infiltration of proximal lymph nodes and vascular structures, as well as metastasis to liver/peritoneum. The first-line agent gemcitabine produced some clinical benefits in the advanced setting but yields a limited disease control, with <15% of patients progression-free at 6 months from diagnosis.

Therefore, the identification of predictive factors seems to be critical for maximizing therapeutic efficacy and minimizing nonfunctional treatment in PDAC. Indeed, the basic science involving surgical, pathological, and gastoenterolocial fields could drive the discovery of new therapeutic approaches against PDAC. Potential topics include, but are not limited to:

  • Pancreatic ductal adenocarcinoma (PDAC)
  • Surgical treatment of pancreatic lesions
  • Preclinical models of PDAC
  • EUS, CT, and MRI in staging
  • Role of neoadjuvant therapy to downstage tumors
  • Palliative therapy such as ERCP and celiac plexus block
  • Precursor lesion such as flat lesions, PanIN, and IPMN
  • Screening for pancreatic cancer in high risk patients (e.g., patients with hereditary pancreatitis and cancer)

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/grp/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/grp/pc/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 809036
  • - Editorial

Pancreatic Cancer

Niccola Funel | Marco Del Chiaro | ... | Johanna Laukkarinen
  • Special Issue
  • - Volume 2014
  • - Article ID 269803
  • - Review Article

Extent of Surgery and Implications of Transection Margin Status after Resection of IPMNs

Marina Paini | Stefano Crippa | ... | Massimo Falconi
  • Special Issue
  • - Volume 2014
  • - Article ID 765451
  • - Review Article

The Utilization of Imaging Features in the Management of Intraductal Papillary Mucinous Neoplasms

Stefano Palmucci | Claudia Trombatore | ... | Antonio Di Cataldo
  • Special Issue
  • - Volume 2014
  • - Article ID 210835
  • - Clinical Study

Hind Right Approach Pancreaticoduodenectomy: From Skill to Indications

Stefan Georgescu | Corina Ursulescu | ... | Cristian Lupascu
  • Special Issue
  • - Volume 2014
  • - Article ID 460363
  • - Research Article

Difference in Early Activation of NF-κB and MCP-1 in Acinar-Cell-Rich versus Fibrotic Human Pancreas Exposed to Surgical Trauma and Hypoxia

Matias Laaninen | Merja Bläuer | ... | Johanna Laukkarinen
  • Special Issue
  • - Volume 2014
  • - Article ID 183852
  • - Review Article

Neoadjuvant Therapy in Pancreatic Cancer: An Emerging Strategy

Alessandro Bittoni | Matteo Santoni | ... | Cascinu Stefano
  • Special Issue
  • - Volume 2014
  • - Article ID 205325
  • - Review Article

High-Intensity Focused Ultrasound Treatment for Advanced Pancreatic Cancer

Yufeng Zhou
  • Special Issue
  • - Volume 2014
  • - Article ID 951957
  • - Research Article

Mast Cells Density Positive to Tryptase Correlates with Angiogenesis in Pancreatic Ductal Adenocarcinoma Patients Having Undergone Surgery

Michele Ammendola | Rosario Sacco | ... | Girolamo Ranieri
  • Special Issue
  • - Volume 2014
  • - Article ID 386561
  • - Review Article

Aberrant MicroRNAs in Pancreatic Cancer: Researches and Clinical Implications

Tao Sun | Xiangyu Kong | ... | Zhaoshen Li
  • Special Issue
  • - Volume 2014
  • - Article ID 414931
  • - Research Article

ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?

Li Pang | Beverly Word | ... | Beverly Lyn-Cook
Gastroenterology Research and Practice
 Journal metrics
Acceptance rate29%
Submission to final decision66 days
Acceptance to publication33 days
CiteScore1.940
Impact Factor1.825
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