Cancers of the upper GI tract require high levels of surgical experience and perioperative management to achieve low complication rates and low mortality. Data show that there is a direct correlation between case load and perioperative mortality particularly for cancers of the esophagus, stomach, liver, bile duct, and pancreas. Short- and long-term survival depends on a variety of factors, which should be considered in this special issue. First of all, the identification of potentially curable patients is crucial. Interdisciplinary conferences discuss the mostly multimodal treatment modalities before onset of treatment. Clinical trials should be included.

Our major interests are all topics that have a correlation with short- and long-term survival. Shortly, diagnostic tools, molecular markers, perioperative chemotherapy or radiation, modern approaches of liver resection and new treatment options for pancreatic cancer.

We invite investigators to submit original articles and reviews of the literature to obtain an actual picture of the topic “upper GI cancer.” Potential topics include, but are not limited to:

• Modern diagnostic tools as part of the multimodal approach
• Recent results in multimodal treatment of esophageal or gastric cancer
• The value of pretherapeutic endoscopic ultrasound in correlation with the effect of neoadjuvant chemotherapy in esophageal and gastric cancer
• New technical approaches of extended liver surgery and long-term survival
• Multimodal therapy of pancreatic cancer
• Complication rate and outcome after surgery
• Novel molecular markers in pancreatic cancer

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/grp/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: