Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding Aldehydes

Table 1

Study of oxidation conditions of benzyl alcohol 1a with RuCpCl(PPh₃)₂.

Entry	Substrate	Solvent	Reaction condition	Product	Yield (%)
1	1a	CH2Cl2	Reflux for 24 h	2a	Trace
2	1a	CH2Cl2	Reflux for 48 h	2a	<10
3	1a	Benzene	Reflux for 24 h	2a	Trace
4	1a	Benzene	Reflux for 48 h	2a	<6
5	1a	Acetone	Reflux for 24 h	2a	Nondetectable
6	1a	Acetone	Reflux for 48 h	2a	Nondetectable
7	1a	THF	Reflux for 24 h	2a	54
8	1a	THF	Reflux for 48 h	2a	71