Reexamining Povarov Reaction’s Scope and Limitation in the Generation of HCV-NS4A Peptidomimetics

Scheme 2

Povarov reactions using aniline (1a), aldehydes (2a-e), and alkenes (3a-f) using a catalyst (Cat). R¹ is absent, because R¹ is assigned to arylamine monomers as mentioned in Scheme 1. In this scheme, only aniline was used as an arylamine.