Organophosphorus chemistry is an evergreen and continually growing field within organic chemistry. It is a vast and exciting field, with potential opportunities for researchers involved in multidisciplinary scientific endeavours, including organic, medicinal, pharmaceutical, agricultural, and industrial chemistry. Organophosphorus compounds find extensive applications in all these fields owing to their inherent physical and biological properties.

Within the field, there have been new developments in many areas, including methodologies, new series of P-compounds, structural modifications for enhanced bioactivity and/or material applications, and many more. To sustain the ongoing developments in this subject, chemists need to face the challenges of designing fascinating reaction protocols and new versions of catalysts for preparing valuable P-compounds satisfying the demands for operation simplicity, cost-effectivity, green aspects, stereoselectivity, and industrial feasibility.

The aim of this Special Issue is to collate research with a focus on the recent advances in multifaceted research activities in organophosphorus chemistry. We welcome original research and review articles that serve to highlight the potential and exciting opportunities of organophosphorus chemistry and will inspire researchers to investigate new problems and find new solutions in this area. Submissions on all aspects of organophosphorus chemistry are welcomed with a focus on exploring the field from both academic and industrial points of view.

This versatile group of compounds with multivalency, variable oxidation states, asymmetry, and metal-binding properties opens up a number of research directions in which we aim to attract submissions. This may include synthetic methods for phosphorus-containing species, including phosphine oxides, phosphinates and phosphonates, sulfide and boron derivatives, 3-, 4-, 5-, 6- and 7-membered heterocycles and bridged heterocycles. Named organic chemical reactions, such as the Wittig- or Wadsworth–Emmons reaction, the Kabachnik–Fields condensation, the Pudovik- or aza-Pudovik addition, the Mitsunobu reaction, or the Hirao cross-coupling, are among the welcome topics. The elaboration of new catalysts, such as phosphonium salts in phase transfer catalysis, or species incorporating transition metals and P-ligands or organocatalysts allowing chemoselective or enantioselective organic chemical transformations belonging to the discipline of green chemistry are also welcomed. The discussion of stereochemical problems and mechanisms evaluated by quantum chemical calculations represent theoretical organic chemistry also fit within the scope of this Issue.

Potential topics include but are not limited to the following:

• Organophosphorus chemistry in general
• The synthesis of tertiary phosphine oxides, phosphinates, and phosphonates
• Preparation of 5-, 6- and 7-membered, as well as bridged P-heterocycles
• Named reactions, such as the Arbuzov-, Perkov-, Kabachik–Fields-, Hirao-, Wittig- and the Mitsunobu reactions
• Sulfur and borane derivatives within organophosphorus compounds
• P-ligands and their transition metal complexes as catalysts
• Phase transfer catalysts and ionic liquids
• Asymmetric catalysis/optical resolution
• Theoretical calculations within organophosphorus chemistry (mechanisms, stereostructures, aromaticity)
• Green aspects in organophosphorus chemistry (e.g. microwave-assisted synthesis, solvent-free reactions, atom-efficient synthesis, and catalytic accomplishments)