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Infectious Diseases in Obstetrics and Gynecology
Volume 1, Issue 3, Pages 144-148
Obstetrics Case Report

Coccidioidal Placentitis With Normal Umbilical Artery Velocimetry

1Divisions of Maternal Fetal Medicine and Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of New Mexico School of Medicine, Albuquerque, NM, USA
2Department of Obstetrics and Gynecology, University of South Carolina, Two Medical Park, Columbia 29203, SC, USA

Received 12 August 1993; Accepted 1 October 1993

Copyright © 1993 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background: Disseminated coccidiomycosis during pregnancy can lead to both maternal and neonatal mortality. Placentitis is an uncommon sequelae and its effect on placental function remains speculative. The present report describes our management of such a case and describes serial umbilical artery velocimetry of an affected placenta.

Case: A pregnant woman with coccidioidal placentitis confirmed histologically was treated with systemic and intrathecal amphotericin B starting at 28 weeks gestation. Serial umbilical artery velocimetry revealed that all systolic/diastolic ratios remained normal, and a normal infant was delivered at term.

Conclusion: Coccidioidal placentitis was successfully treated with amphotericin B; serial umbilical artery velocimetry monitoring exhibited no abnormalities and, along with other reassuring fetal parameters, allowed continuation of the pregnancy to term.