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Infectious Diseases in Obstetrics and Gynecology
Volume 2 (1995), Issue 5, Pages 218-222
Clinical Study

Repeated Recovery of Staphylococcus saprophyticus From the Urogenital Tracts of Women: Persistence Vs. Recurrence

1Department of Internal Medicine, University of Nebraska Medical Center, 600 S. 42nd Street, Omaha, NE 68198-5400, USA
2Department of Medical Microbiology, Creighton University School of Medicine, Omaha, NE, USA

Received 23 September 1994; Accepted 13 January 1995

Copyright © 1995 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective: The purpose of this study was to determine whether colonization was persistent or recurrent in a small group of women who had repeated recovery of Staphylococcus saprophyticus from their urogenital tracts.

Methods: Paired isolates of S. saprophyticus from each of the study subjects were genotypically typed by plasmid fingerprinting and comparison of chromosomal-DNA restriction fragment-length polymorphism patterns by field-inversion gel electrophoresis (FIGE) and contour-clamped homogenous electric-field (CHEF) electrophoresis.

Results: All isolates of S. saprophyticus from the study subjects were classified as genetically unique by each of the typing methods.

Conclusions: The subjects experienced recurrent colonization with different isolates of S. saprophyticus. These findings may have broader implications regarding the pathogenesis and recurrence of S. saprophyticus urinary-tract infection.