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Infectious Diseases in Obstetrics and Gynecology
Volume 5, Issue 6, Pages 380-385
Obstetrical Case Report

Vertical Transmission of Herpes Simplex Virus Acquired After Primary Outbreak in Second Trimester of a Dichorionic Twin Gestation

1Lovelace Medical Center, Albuquerque, NM, USA
2Department of OB-GYN, 5400 Gibson Blvd., S.E.,, Albuquerque 87108, NM, USA

Received 24 November 1997; Accepted 3 February 1998

Copyright © 1997 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background: The incidence of genital herpes simplex virus (HSV) has increased in recent years, particularly among women of reproductive age. This places more neonates at risk for severe morbidity and mortality. Treatment recommendations for primary disease in pregnancy are lacking, particularly for those who acquire. HSV remote from term.

Case: A patient at 17 weeks of gestation carrying dichorionic twins developed primary herpes with subsequent vertical transmission of the virus and significant neonatal morbidity.

Conclusion: Data regarding risks and benefits of treatments such as acyclovir and immunoprophylaxis are lacking at a time when the incidence of HSV infection is on the rise.